Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.75 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.66 |
| ▸ | GABRP | O00591 | 2/20 | 0.64 |
| ▸ | GABRD | O14764 | 2/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.64 |
| ▸ | GABRE | P78334 | 2/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.64 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.64 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.64 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29861461 | 0.91 | AR (0.87) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL547539 | 0.91 | AR (0.87) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21788420 | 0.90 | AR (0.73) | ARABCG2GABRPGABRDGABRA1 | |
| SCHEMBL17107302 | 0.90 | AR (0.85) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15661295 | 0.90 | AR (0.85) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21788615 | 0.90 | AR (0.81) | ARABCG2GABRPGABRDGABRA1 | |
| SCHEMBL1715991 | 0.89 | AR (0.73) | ARABCG2GABRPGABRDGABRA1 | |
| SCHEMBL30184881 | 0.89 | AR (0.73) | ARABCG2GABRPGABRDGABRA1 | |
| SCHEMBL29378261 | 0.89 | AR (0.87) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL547156 | 0.89 | AR (0.87) | ARGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066440-A9 | TREATMENT OF BREAST CANCER | MEDIVATION PROSTATE THERAPEUTICS, INC. (US) | 2013-07-18 | — | — | WO | disclosed |
| WO-2013066440-A1 | TREATMENT OF BREAST CANCER | MEDIVATION PROSTATE THERAPEUTICS, INC. (US) | 2013-05-10 | — | — | WO | disclosed |