Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 13/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934391 | 0.85 | ALDH1A1 (0.60) | USP2CYP3A4CYP1A2CYP2C19ALOX15 | |
| SCHEMBL14934392 | 0.81 | USP2 (0.68) | USP2CYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL17101972 | 0.79 | USP2 (1.00) | USP2CYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL14934529 | 0.78 | EPHX2 (0.63) | USP2CYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL14934576 | 0.78 | FAAH (0.67) | USP2CYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL23849996 | 0.76 | ALDH1A1 (0.47) | USP2CYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL14934582 | 0.76 | EPHX2 (0.63) | USP2CYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL14934475 | 0.76 | EPHX2 (0.72) | USP2CYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL14934481 | 0.76 | EPHX2 (0.69) | USP2CYP3A4CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL2724878 | 0.75 | TRPV1 (0.63) | SMN1; SMN2EPHX2TRPM8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |