Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16141363 | 1.00 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BSLC18A2 | |
| SCHEMBL16143196 | 0.86 | SLC18A2 (0.54) | ADRA1DADRA1AADRA1BSLC18A2 | |
| SCHEMBL14920711 | 0.84 | PRCP (0.52) | — | |
| SCHEMBL31449822 | 0.83 | KDM4E (0.45) | ADRA1DADRA1AADRA1BSLC18A2 | |
| SCHEMBL14920858 | 0.80 | — | — | |
| SCHEMBL2198153 | 0.79 | SLC18A2 (0.43) | SLC18A2 | |
| SCHEMBL16109199 | 0.77 | MEN1 (0.48) | — | |
| SCHEMBL5729259 | 0.77 | MEN1 (0.48) | — | |
| SCHEMBL16141349 | 0.77 | CHRM2 (0.57) | — | |
| SCHEMBL31449598 | 0.77 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630929-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2017-04-25 | — | — | US | disclosed |
| EP-2773637-B1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2016-06-08 | — | — | EP | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |