Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653708 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRP2RX7HTTLMNA | |
| SCHEMBL11638648 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TSHRP2RX7HTTLMNA | |
| SCHEMBL1493508 | 0.83 | KCNN4 (0.44) | ALDH1A1TSHRKCNN4 | |
| SCHEMBL1493409 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRHTTLMNANPSR1 | |
| SCHEMBL28299784 | 0.77 | ALDH1A1 (0.79) | ALDH1A1TSHRHTTLMNAKCNN4 | |
| SCHEMBL28879265 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRP2RX7HTTLMNA | |
| SCHEMBL1537920 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRP2RX7LMNANPSR1 | |
| SCHEMBL1493493 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRP2RX7HTTLMNA | |
| SCHEMBL1493503 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHRHTTLMNANPSR1 | |
| SCHEMBL1493397 | 0.72 | P2RX7 (0.52) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056920-A | Tetrazole compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2011-05-11 | — | — | CN | disclosed |
| US-20110086889-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-04-14 | — | — | US | disclosed |
| EP-2288603-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009150614-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-12-17 | — | — | WO | disclosed |
| EP-0657297-B2 | Security document having a transparent or translucent support and containing interference pigments. | AGFA GEVAERT (BE) | 2003-04-23 | — | — | EP | disclosed |
| US-6284350-B1 | HAVING VISUAL PERSONIFIED MARK OF THE OWNER | AGFA-GEVAERT (BE) | 2001-09-04 | — | — | US | disclosed |
| US-6250554-B1 | Chip card comprising an imaged-receiving layer | AGFA-GEVAERT (BE) | 2001-06-26 | — | — | US | disclosed |
| US-6210777-B1 | Security document having a transparent or translucent support and containing interference pigments | AGFA-GEVAERT (BE) | 2001-04-03 | — | — | US | disclosed |
| EP-1033258-A1 | Security document consisting of a laminate | AGFA-GEVAERT N.V. (BE) | 2000-09-06 | — | — | EP | disclosed |
| EP-0977083-A1 | An optical card comprising an imaged layer | AGFA-GEVAERT N.V. (BE) | 2000-02-02 | — | — | EP | disclosed |
| EP-0557616-A1 | A silver halide material suitable for use in a silver salt diffusion transfer process | AGFA-GEVAERT N.V. (BE) | 1993-09-01 | — | — | EP | disclosed |
| EP-0554930-A1 | A silver halide material suitable for use in a silver salt diffusion transfer process | AGFA-GEVAERT N.V. (BE) | 1993-08-11 | — | — | EP | disclosed |
| EP-0546599-A1 | An image receiving material for use in the silver salt diffusion transfer process | AGFA-GEVAERT N.V. (BE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0546598-A1 | Image receiving layer for use in a silver salt diffusion transfer process | AGFA-GEVAERT N.V. (BE) | 1993-06-16 | — | — | EP | disclosed |
| US-5204212-A | Phosphate-free; development nuclei in receiving layer | AGFA-GEVAERT, N.V. (BE) | 1993-04-20 | — | — | US | disclosed |
| EP-0527521-A1 | A silver halide photographic material | AGFA-GEVAERT N.V. (BE) | 1993-02-17 | — | — | EP | disclosed |
| US-5162192-A | Methylethanolamines | AGFA-GEVAERT, N.V. (BE) | 1992-11-10 | — | — | US | disclosed |
| EP-0496126-A1 | A processing liquid for the silver salt diffusion transfer process | AGFA-GEVAERT N.V. (BE) | 1992-07-29 | — | — | EP | disclosed |
| EP-0398435-A1 | Liquid for DTR-photography | AGFA-GEVAERT N.V. (BE) | 1990-11-22 | — | — | EP | disclosed |
| EP-0397926-A1 | Processing liquid for use in silver halide photography | AGFA-GEVAERT N.V. (BE) | 1990-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086889-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | HCRTR2, HCRTR1, NPY1R | ALDH1A1 3233/4885TSHR 44/4885P2RX7 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.