Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686477 | 1.00 | HTR2A (0.49) | HTR2AHRH1F2PRSS1EPHX2 | |
| SCHEMBL1967142 | 0.91 | HTR2A (0.56) | HTR2AHRH1EPHX2SIGMAR1MAPT | |
| SCHEMBL11934865 | 0.89 | SIGMAR1 (0.54) | HTR2AHRH1SIGMAR1ALDH1A1 | |
| SCHEMBL13438744 | 0.89 | SIGMAR1 (0.54) | HTR2AHRH1SIGMAR1ALDH1A1 | |
| SCHEMBL17667739 | 0.84 | EPHX2 (0.58) | HTR2AHRH1EPHX2SIGMAR1MAPT | |
| SCHEMBL4929477 | 0.83 | CXCR4 (0.59) | HTR2ASIGMAR1NPC1CYP3A4CYP2D6 | |
| SCHEMBL21257794 | 0.83 | EPHX2 (0.65) | HTR2AHRH1EPHX2SIGMAR1MAPT | |
| SCHEMBL10032819 | 0.83 | EPHX2 (0.65) | HTR2AHRH1EPHX2SIGMAR1MAPT | |
| SCHEMBL4929472 | 0.83 | CXCR4 (0.59) | HTR2ASIGMAR1NPC1CYP3A4CYP2D6 | |
| SCHEMBL4073277 | 0.81 | SIGMAR1 (0.64) | HTR2AHRH1SIGMAR1SMN1; SMN2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066684-A1 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals, LLC (US) | 2013-05-10 | — | — | WO | disclosed |