Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.33 |
| ▸ | GABRP | O00591 | 4/20 | 0.33 |
| ▸ | GABRD | O14764 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.33 |
| ▸ | GABRE | P78334 | 4/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16139576 | 0.77 | PDE2A (0.36) | ALDH1A1POLBSMN1; SMN2GABRA2GABRB2 | |
| SCHEMBL11016366 | 0.77 | PDE2A (0.36) | ALDH1A1KDM4EPOLBSMN1; SMN2PLAU | |
| SCHEMBL16735777 | 0.73 | ALDH1A1 (0.33) | ALDH1A1KDM4ESMN1; SMN2PDE2ACYP3A4 | |
| SCHEMBL5202584 | 0.73 | TSHR (0.36) | ALDH1A1CYP3A4GAATSHRCA1 | |
| SCHEMBL2085234 | 0.71 | RAPGEF4 (0.33) | ALDH1A1PDE2ACYP3A4TSHRHPGD | |
| SCHEMBL24241149 | 0.68 | MAPK1 (0.42) | ALDH1A1KDM4ESMN1; SMN2GABRA2GABRB2 | |
| SCHEMBL30439201 | 0.68 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBSMN1; SMN2PLAU | |
| SCHEMBL967220 | 0.68 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBSMN1; SMN2PLAU | |
| Hydrochloric Acid SCHEMBL29123267 | 0.66 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBSMN1; SMN2PLAU | |
| SCHEMBL10431590 | 0.66 | AR (0.33) | ALDH1A1KDM4EKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064521-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |