SCHEMBL14934980

SCHEMBL14934980

Nc1ncc(C2CC2(F)F)cc1Cl

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAP3K12 Q12852 6/20 0.37
CPB2 Q96IY4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24737528 0.79 HTT (0.46)
SCHEMBL16139573 0.79 CHRNB2 (0.37)
SCHEMBL31658598 0.79 HTT (0.46)
SCHEMBL29830941 0.74 KDM4E (0.38) MAP3K12
SCHEMBL14934977 0.74 KDM4E (0.38) MAP3K12
SCHEMBL23535126 0.74 MAP4K4 (0.31)
SCHEMBL23534412 0.74
SCHEMBL21728894 0.73 CYP3A4 (0.43)
SCHEMBL20519883 0.71 HRH1 (0.30)
SCHEMBL14934982 0.70 KDM1A (0.36) MAP3K12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013064521-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2013-05-10 WO disclosed