Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20838112 | 0.88 | HDAC4 (0.74) | HDAC6HDAC4HDAC1HDAC8 | |
| SCHEMBL19994696 | 0.88 | HDAC4 (0.69) | HDAC6HDAC4ALDH1A1HDAC1HDAC8 | |
| SCHEMBL20593540 | 0.87 | HDAC4 (0.71) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL20593509 | 0.87 | HDAC6 (0.76) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL14935019 | 0.87 | HDAC6 (0.76) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL20593259 | 0.86 | HDAC4 (0.69) | HDAC6HDAC4ALDH1A1HDAC1HDAC8 | |
| SCHEMBL14935042 | 0.86 | HDAC4 (0.69) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL23013577 | 0.85 | HDAC6 (0.53) | HDAC6HDAC4ALDH1A1HDAC1HDAC8 | |
| SCHEMBL20593472 | 0.85 | HDAC6 (0.62) | HDAC6HDAC4ALDH1A1HDAC1HDAC8 | |
| SCHEMBL20497065 | 0.85 | HDAC6 (0.67) | HDAC6HDAC4HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066835-A2 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |