Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935014 | 0.88 | HDAC6 (0.71) | HDAC4HDAC6ALDH1A1HDAC1HDAC8 | |
| SCHEMBL18840097 | 0.86 | HDAC4 (0.69) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL14935021 | 0.86 | HDAC4 (0.72) | HDAC4KMT2AMEN1HDAC6HDAC1 | |
| SCHEMBL23013746 | 0.83 | MAPT (0.51) | HDAC4KMT2AMEN1TP53HDAC6 | |
| SCHEMBL21903446 | 0.82 | HDAC4 (0.78) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL14645419 | 0.82 | HDAC4 (1.00) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL15920066 | 0.81 | KMT2A (1.00) | KMT2AMEN1TP53MAPTHSD17B10 | |
| SCHEMBL10554316 | 0.81 | HDAC4 (0.64) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL14645766 | 0.81 | HDAC4 (0.75) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL7296994 | 0.80 | HDAC6 (0.59) | HDAC4TP53HDAC6MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515908-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018055135-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-29 | — | — | WO | disclosed |