SCHEMBL14935155

SCHEMBL14935155

OCCC(O)(Cc1ccc(Cl)cc1)Cc1ccc(Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.45
SLC6A2 P23975 1/20 0.45
HTR2A P28223 1/20 0.45
HRH1 P35367 1/20 0.45
HTR2B P41595 1/20 0.45
CHRNA4 P43681 1/20 0.45
SLC6A3 Q01959 1/20 0.45
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
KCNH2 Q12809 1/20 0.41
IDO1 P14902 3/20 0.38
CYP3A4 P08684 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14935113 0.79 TAAR1 (0.35) HTR2AALDH1A1IDO1MEN1KMT2A
SCHEMBL14935111 0.78 CYP2C19 (0.50) SLC6A2LMNAIDO1CYP3A4CYP1A2
SCHEMBL11141219 0.73 SLC6A4 (0.52) SLC6A4SLC6A2HTR2AHRH1HTR2B
SCHEMBL14935124 0.72 TSHR (0.58) ALDH1A1KCNH2IDO1CYP1A2CYP2C9
SCHEMBL5873468 0.71 SLC6A4 (0.61) SLC6A4SLC6A2HTR2AHRH1HTR2B
SCHEMBL14935121 0.71 SLC6A4 (0.50) SLC6A4SLC6A2HTR2AHRH1HTR2B
SCHEMBL11670635 0.70 SLC6A4 (0.59) SLC6A4SLC6A2HTR2AHRH1HTR2B
SCHEMBL11141004 0.70 SLC6A4 (0.59) SLC6A4SLC6A2HTR2AHRH1HTR2B
SCHEMBL11613943 0.69 SLC6A4 (0.44) SLC6A4SLC6A2HTR2AHRH1HTR2B
SCHEMBL21177760 0.68 SLC6A4 (0.57) SLC6A4SLC6A2HTR2AHRH1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10197881-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2019-02-05 US disclosed
US-20170184936-A1 Complimentary Polymer Electrochromic Device ASHWIN-USHAS CORP INC (US) 2017-06-29 US disclosed
EP-2780762-B1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORP INC (US) 2017-06-28 EP disclosed
US-9594284-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2017-03-14 US disclosed
US-9274395-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2016-03-01 US disclosed
US-20150275385-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN USHAS CORP INC (US) 2015-10-01 US disclosed
EP-2780762-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE Ashwin-Ushas Corporation, Inc. (US) 2014-09-24 EP disclosed
WO-2013074702-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORPORATION, INC. (US) 2013-05-23 WO disclosed
US-20130120821-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORPORATION, INC. (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10197881-B2 Complimentary polymer electrochromic device PMS2, PARG, EED SLC6A4 4607/4885SLC6A2 3924/4885HTR2A 1863/4885
US-20130120821-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE PMS2, PARG, EED SLC6A4 4607/4885SLC6A2 3924/4885HTR2A 1863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.