Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CDC7 | O00311 | 1/20 | 0.57 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384455 | 0.98 | GSK3B (0.75) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL5381426 | 0.91 | GSK3B (0.78) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL5376063 | 0.87 | GSK3B (0.76) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL4822785 | 0.85 | GSK3B (0.84) | GSK3BKMT2ACDC7DBF4MAPT | |
| SCHEMBL5381549 | 0.84 | GSK3B (1.00) | GSK3BCDC7DBF4MAPTGAA | |
| SCHEMBL2239607 | 0.84 | CYP2A6 (0.59) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL29310490 | 0.82 | GSK3B (0.79) | GSK3BKMT2ACDC7DBF4MAPT | |
| SCHEMBL5385544 | 0.79 | GSK3B (0.64) | GSK3BKMT2ACDC7DBF4MAPT | |
| SCHEMBL5400045 | 0.78 | GSK3B (0.69) | GSK3BKMT2ACYP19A1HPGDXDH | |
| SCHEMBL14935661 | 0.78 | GSK3B (0.55) | GSK3BKMT2ACDC7DBF4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123281-A1 | Compositions and Methods for Inhibition of TBL-1 Binding to Disease-Associated Molecules | BETA CAT PHARMACEUTICALS, LLC (US) | 2013-05-16 | — | — | US | disclosed |
| WO-2013071232-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF TBL-1 BINDING TO DISEASE-ASSOCIATED MOLECULES | BETA CAT PHARMACEUTICALS, LLC (US) | 2013-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123281-A1 | Compositions and Methods for Inhibition of TBL-1 Binding to Disease-Associated Molecules | TBL2, TBL3, TBL1XR1 | GSK3B 752/4885KMT2A 4037/4885CDC7 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.