Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | CDC7 | O00311 | 1/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.46 |
| ▸ | RAF1 | P04049 | 3/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384455 | 0.80 | GSK3B (0.75) | GSK3BCDC7DBF4GAAMAPT | |
| SCHEMBL14935666 | 0.79 | GSK3B (0.73) | GSK3BCDC7DBF4GAAMAPT | |
| SCHEMBL5385542 | 0.79 | RAF1 (0.46) | GSK3BCDC7GAAMAPTPTGES | |
| SCHEMBL5381549 | 0.79 | GSK3B (1.00) | GSK3BCDC7DBF4GAAMAPT | |
| SCHEMBL4822785 | 0.76 | GSK3B (0.84) | GSK3BCDC7DBF4GAAMAPT | |
| SCHEMBL5381426 | 0.76 | GSK3B (0.78) | GSK3BCDC7DBF4GAAMAPT | |
| SCHEMBL5390578 | 0.76 | GSK3B (0.67) | GSK3BKMT2AMEN1 | |
| SCHEMBL29310490 | 0.74 | GSK3B (0.79) | GSK3BCDC7DBF4GAAMAPT | |
| SCHEMBL31074768 | 0.72 | MEN1 (0.49) | MAPTKMT2AHPGDL3MBTL1MEN1 | |
| SCHEMBL5376063 | 0.72 | GSK3B (0.76) | GSK3BCDC7DBF4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |