Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 9/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12757999 | 1.00 | PIN1 (0.40) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL3725157 | 0.84 | PIN1 (0.40) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL5502343 | 0.84 | PIN1 (0.40) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL5207017 | 0.84 | PIN1 (0.40) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL10110426 | 0.84 | PIN1 (0.42) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL756230 | 0.84 | PIN1 (0.40) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL1494292 | 0.84 | ATM (0.38) | PEPDXPNPEP1DPP4DPP8DPP7 | |
| SCHEMBL28324022 | 0.79 | PIN1 (0.43) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL1155369 | 0.79 | PIN1 (0.43) | PIN1CNR2PEPDXPNPEP1DPP4 | |
| SCHEMBL30874818 | 0.78 | PIN1 (0.51) | PIN1CNR2PEPDXPNPEP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013011887-A1 | METHOD FOR PRODUCING (2S, 4S)-1-HYDROXYACETYL-2-AMINOCARBONYL-4-FLUOROPYRROLIDINE | セントラル硝子株式会社 (JP) | 2013-01-24 | — | — | WO | disclosed |
| US-7915427-B2 | Process for producing aminoacetyl pyrrolidine carbonitrile derivative and intermediate for production thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20090048454-A1 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1995237-A1 | METHOD FOR PRODUCING AMINOACETYLPYRROLIDINECARBONITRILE DERIVATIVE AND PRODUCTION INTERMEDIATE THEREOF | Kyorin Pharmaceutical Co., Ltd. (JP) | 2008-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048454-A1 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof | CBR3, CPS1, CBR1 | PIN1 1115/4885CNR2 105/4885PEPD 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.