Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 6/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756230 | 1.00 | PIN1 (0.40) | PIN1CNR2MAOAMAOBPEPD | |
| SCHEMBL3725157 | 1.00 | PIN1 (0.40) | PIN1CNR2MAOAMAOBPEPD | |
| SCHEMBL1334680 | 0.84 | DPP4 (0.34) | PEPDXPNPEP1DPP4DPP8DPP9 | |
| SCHEMBL1336107 | 0.84 | DPP4 (0.34) | PEPDXPNPEP1DPP4DPP8DPP9 | |
| SCHEMBL1334552 | 0.84 | DPP4 (0.34) | PEPDXPNPEP1DPP4DPP8DPP9 | |
| SCHEMBL1334677 | 0.84 | DPP4 (0.34) | PEPDXPNPEP1DPP4DPP8DPP9 | |
| SCHEMBL1334675 | 0.84 | DPP4 (0.34) | PEPDXPNPEP1DPP4DPP8DPP9 | |
| SCHEMBL1493709 | 0.84 | PIN1 (0.40) | PIN1CNR2MAOAMAOBPEPD | |
| SCHEMBL12757999 | 0.84 | PIN1 (0.40) | PIN1CNR2MAOAMAOBPEPD | |
| SCHEMBL10110426 | 0.83 | PIN1 (0.42) | PIN1CNR2PEPDXPNPEP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737863-A2 | 2-CYANOPYRROLIDINECARBOXAMIDES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | Astellas Pharma Inc. (JP) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005042533-A2 | 2-CYANOPYRROLIDINECARBOXAMIDES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2005-05-12 | — | — | WO | disclosed |