SCHEMBL14937404

SCHEMBL14937404

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nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TDP1 Q9NUW8 1/20 0.55
PDE4A P27815 1/20 0.46
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
TOP1 P11387 1/20 0.33
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23647592 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL9811639 0.92 LMNA (0.53) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL17200647 0.92 LMNA (0.53) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL5575310 0.80
SCHEMBL7718568 0.80
SCHEMBL2772175 0.80
Sorbitol SCHEMBL296124 0.80 LMNA (0.92) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL6264130 0.80 LMNA (0.92) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL28441266 0.78 LMNA (0.65) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL20594082 0.76 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013103909-A1 HIGH CAPACITY OXOANION CHELATING MEDIA FROM HYPERBRANCHED MACROMOLECULES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-07-11 WO claimed
US-20130118986-A1 High Capacity Oxoanion Chelating Media From Hyperbranched Macromolecules NATIONAL SCIENCE FOUNDATION 2013-05-16 US claimed
CN-117924531-A High-purity low-molecular-weight astragalus polysaccharide, and preparation method and application thereof 首都医科大学附属北京友谊医院 2024-04-26 CN disclosed