Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 13/20 | 0.67 |
| ▸ | RAB9A | P51151 | 10/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734168 | 0.86 | SMN1; SMN2 (0.80) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL4734171 | 0.86 | SMN1; SMN2 (0.80) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL20520189 | 0.86 | SMN1; SMN2 (0.80) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL4554299 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL14938472 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL23678214 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL20205815 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL23658108 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL7449894 | 0.79 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL17206744 | 0.79 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |