Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 14/20 | 0.80 |
| ▸ | MAPT | P10636 | 14/20 | 0.80 |
| ▸ | RAB9A | P51151 | 11/20 | 0.80 |
| ▸ | NPC1 | O15118 | 8/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734168 | 1.00 | SMN1; SMN2 (0.80) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL4734171 | 1.00 | SMN1; SMN2 (0.80) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL7449894 | 0.92 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL17206744 | 0.92 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL14938579 | 0.86 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL4554993 | 0.86 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL4554299 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL17206746 | 0.81 | SMN1; SMN2 (0.87) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL665621 | 0.80 | KDM1A (0.62) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL665622 | 0.80 | KDM1A (0.62) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180284095-A1 | BIOMARKERS ASSOCIATED WITH LSD1 INHIBITORS AND USES THEREOF | ORYZON GENOMICS SA (ES) | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180284095-A1 | BIOMARKERS ASSOCIATED WITH LSD1 INHIBITORS AND USES THEREOF | KDM1B, EZH2, DOT1L | SMN1; SMN2 1946/4885MAPT 2058/4885RAB9A 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.