Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938620 | 1.00 | GAA (0.48) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL30616243 | 0.80 | ALDH1A1 (0.50) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL14938455 | 0.79 | MAPT (0.64) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL14938436 | 0.75 | ALDH1A1 (0.51) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL14938510 | 0.75 | ALDH1A1 (0.48) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3065930 | 0.75 | RAB9A (0.64) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14938458 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8877445 | 0.74 | ALDH1A1 (0.44) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL14950318 | 0.73 | RAB9A (0.69) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL14950270 | 0.72 | CYP1A2 (0.44) | GAASMN1; SMN2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |