Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15969807 | 0.92 | INSR (0.62) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14950371 | 0.90 | INSR (0.60) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14938639 | 0.88 | INSR (0.55) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14938551 | 0.86 | INSR (0.55) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16180826 | 0.86 | INSR (0.60) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14938756 | 0.85 | INSR (0.44) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8388983 | 0.82 | INSR (0.77) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12258217 | 0.80 | INSR (0.61) | INSRALDH1A1MMP14HSD17B10MAPK1 | |
| SCHEMBL15970602 | 0.80 | INSR (0.57) | INSRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14941470 | 0.78 | KMT2A (0.56) | INSRMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776000-B1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2016-03-02 | — | — | EP | claimed |
| US-8864848-B2 | Zwitterionic azo dyestuffs for coloring keratin-including fibres | HENKEL AG & CO. KGAA (DE) | 2014-10-21 | — | — | US | claimed |
| EP-2776000-A1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel AG & Co. KGaA (DE) | 2014-09-17 | — | — | EP | claimed |
| US-20140237735-A1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-INCLUDING FIBRES | HENKEL AG & CO. KGAA (DE) | 2014-08-28 | — | — | US | claimed |
| WO-2013068223-A1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO. KGAA (DE) | 2013-05-16 | — | — | WO | claimed |
| EP-2776000-B1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2016-03-02 | — | — | EP | disclosed |
| US-9029362-B2 | Iminothiadiazine dioxide compounds as brace inhibitors, compositions, and their use | MERCK SHARP & DOHME CORP. (US) | 2015-05-12 | — | — | US | disclosed |
| US-8864848-B2 | Zwitterionic azo dyestuffs for coloring keratin-including fibres | HENKEL AG & CO. KGAA (DE) | 2014-10-21 | — | — | US | disclosed |
| EP-2776000-A1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel AG & Co. KGaA (DE) | 2014-09-17 | — | — | EP | disclosed |
| US-20140237735-A1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-INCLUDING FIBRES | HENKEL AG & CO. KGAA (DE) | 2014-08-28 | — | — | US | disclosed |
| WO-2013068223-A1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO. KGAA (DE) | 2013-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140237735-A1 | ZWITTERIONIC AZO DYESTUFFS FOR COLOURING KERATIN-INCLUDING FIBRES | KRT18, IK, ZW10 | INSR 4377/4885MEN1 1358/4885KMT2A 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.