Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939013 | 0.89 | NPSR1 (0.64) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14939270 | 0.87 | NPSR1 (0.61) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14939418 | 0.87 | NPSR1 (0.61) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14940377 | 0.86 | NPSR1 (0.74) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14939967 | 0.86 | NPSR1 (0.57) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14939276 | 0.85 | NPSR1 (0.59) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14940230 | 0.84 | NPSR1 (0.55) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14939954 | 0.83 | NPSR1 (0.82) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14938958 | 0.83 | NPSR1 (0.56) | NPSR1MAPTMEN1KMT2ASIGMAR1 | |
| SCHEMBL14939278 | 0.83 | NPSR1 (0.56) | NPSR1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |