Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939617 | 0.92 | NPSR1 (1.00) | NPSR1MAPTSIGMAR1MMP2MMP9 | |
| SCHEMBL14939954 | 0.88 | NPSR1 (0.82) | NPSR1MAPTSIGMAR1MMP2MMP9 | |
| SCHEMBL14940217 | 0.88 | NPSR1 (0.82) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939425 | 0.86 | NPSR1 (0.79) | NPSR1MAPTSIGMAR1MMP2MMP9 | |
| SCHEMBL14939838 | 0.85 | NPSR1 (0.73) | NPSR1MAPTSIGMAR1MMP2MMP9 | |
| SCHEMBL14940377 | 0.83 | NPSR1 (0.74) | NPSR1MAPTSIGMAR1LMNACHRM3 | |
| SCHEMBL14939742 | 0.83 | NPSR1 (0.82) | NPSR1MAPTSIGMAR1MMP2MMP9 | |
| SCHEMBL14939688 | 0.83 | NPSR1 (0.77) | NPSR1MAPTSIGMAR1MMP2MMP9 | |
| SCHEMBL14939947 | 0.80 | NPSR1 (0.77) | NPSR1MAPTSIGMAR1LMNACHRM2 | |
| SCHEMBL14939435 | 0.80 | NPSR1 (0.77) | NPSR1MAPTLMNACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |