Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939106 | 0.93 | NPSR1 (0.64) | NPSR1MAPTLMNATP53GRIN2B | |
| SCHEMBL14940268 | 0.92 | NPSR1 (0.53) | NPSR1MAPTLMNATP53GRIN2B | |
| SCHEMBL14940008 | 0.92 | NPSR1 (0.56) | NPSR1MAPTLMNATP53HTR7 | |
| SCHEMBL14939396 | 0.92 | NPSR1 (0.51) | NPSR1MAPTLMNATP53GRIN2B | |
| SCHEMBL14940165 | 0.92 | NPSR1 (0.51) | NPSR1MAPTLMNATP53GRIN2B | |
| SCHEMBL14940141 | 0.92 | NPSR1 (0.54) | NPSR1MAPTLMNATP53GRIN2B | |
| SCHEMBL14940323 | 0.90 | TP53 (0.54) | NPSR1MAPTLMNATP53GRIN2B | |
| SCHEMBL14939128 | 0.89 | NPSR1 (0.50) | NPSR1MAPTLMNATP53HTR7 | |
| SCHEMBL14939636 | 0.89 | MAPT (0.54) | NPSR1MAPTLMNATP53GRIN2B | |
| SCHEMBL14940061 | 0.89 | NPSR1 (0.57) | NPSR1MAPTLMNATP53HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |