Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938954 | 0.87 | NPSR1 (0.76) | NPSR1MMP2MMP9MAPTSIGMAR1 | |
| SCHEMBL14939432 | 0.87 | NPSR1 (0.68) | NPSR1MMP2MMP9MAPTSIGMAR1 | |
| SCHEMBL14940030 | 0.87 | NPSR1 (0.68) | NPSR1MMP2MMP9MAPTSIGMAR1 | |
| SCHEMBL14940534 | 0.86 | NPSR1 (0.49) | NPSR1MAPT | |
| SCHEMBL14940152 | 0.85 | NPSR1 (0.48) | NPSR1MAPT | |
| SCHEMBL14939709 | 0.85 | NPSR1 (0.77) | NPSR1MMP2MMP9MAPTSIGMAR1 | |
| SCHEMBL14939978 | 0.83 | NPSR1 (0.47) | NPSR1MAPT | |
| SCHEMBL14939690 | 0.83 | NPSR1 (0.77) | NPSR1MMP2MMP9MAPT | |
| SCHEMBL14939707 | 0.82 | NPSR1 (0.68) | NPSR1MMP2MMP9MAPTSIGMAR1 | |
| SCHEMBL14939617 | 0.82 | NPSR1 (1.00) | NPSR1MMP2MMP9MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |