Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940356 | 0.87 | NPSR1 (0.54) | NPSR1MAPTLMNAKDM4ETDP1 | |
| SCHEMBL14940176 | 0.85 | NPSR1 (0.52) | NPSR1LMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL14940014 | 0.85 | NPSR1 (0.51) | NPSR1MAPTLMNAKDM4ETDP1 | |
| SCHEMBL14939709 | 0.85 | NPSR1 (0.77) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939617 | 0.84 | NPSR1 (1.00) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939425 | 0.84 | NPSR1 (0.79) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939840 | 0.83 | NPSR1 (0.77) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939933 | 0.83 | NPSR1 (0.77) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939576 | 0.83 | NPSR1 (0.48) | NPSR1MAPTKDM4ETACR1ALDH1A1 | |
| SCHEMBL14940320 | 0.82 | NPSR1 (0.72) | NPSR1MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |