Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940099 | 0.92 | NPSR1 (0.55) | NPSR1MAPTALDH1A1LMNARIPK1 | |
| SCHEMBL14939180 | 0.91 | NPSR1 (0.50) | NPSR1MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14939013 | 0.89 | NPSR1 (0.64) | NPSR1MAPTALDH1A1LMNARIPK1 | |
| SCHEMBL14940230 | 0.89 | NPSR1 (0.55) | NPSR1MAPTALDH1A1LMNARIPK1 | |
| SCHEMBL14939105 | 0.88 | NPSR1 (0.51) | NPSR1MAPTALDH1A1LMNARIPK1 | |
| SCHEMBL14939492 | 0.86 | NPSR1 (0.53) | NPSR1MAPTALDH1A1LMNARIPK1 | |
| SCHEMBL14939266 | 0.86 | MAPT (0.55) | NPSR1MAPTALDH1A1SIGMAR1DRD2 | |
| SCHEMBL14939874 | 0.85 | NPSR1 (0.48) | NPSR1MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14939155 | 0.84 | NPSR1 (0.54) | NPSR1MAPTALDH1A1LMNARIPK1 | |
| SCHEMBL14940311 | 0.84 | NPSR1 (0.51) | NPSR1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |