Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939267 | 0.92 | NPSR1 (0.47) | NPSR1MAPTMTNR1BHTR7TP53 | |
| SCHEMBL14939335 | 0.91 | TP53 (0.48) | NPSR1MAPTHTR7TP53ALDH1A1 | |
| SCHEMBL14939956 | 0.91 | NPSR1 (0.47) | NPSR1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL14939287 | 0.90 | NPSR1 (0.46) | NPSR1MAPTMTNR1BHTR7TP53 | |
| SCHEMBL14940099 | 0.89 | NPSR1 (0.55) | NPSR1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL14939450 | 0.88 | NPSR1 (0.52) | NPSR1MAPTHTR7TP53ALDH1A1 | |
| SCHEMBL14939105 | 0.87 | NPSR1 (0.51) | NPSR1MAPTHTR7TP53ALDH1A1 | |
| SCHEMBL14939013 | 0.87 | NPSR1 (0.64) | NPSR1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL14940230 | 0.86 | NPSR1 (0.55) | NPSR1MAPTHTR7ALDH1A1KDM4E | |
| SCHEMBL14939616 | 0.85 | NPSR1 (0.51) | NPSR1MAPTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |