Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939941 | 0.93 | KMT2A (0.47) | KMT2ACYP2A13LMNAHTR7ACHE | |
| SCHEMBL14939368 | 0.91 | KDM4E (0.49) | KMT2ACYP2A13LMNAACHERAB9A | |
| SCHEMBL14939578 | 0.90 | KMT2A (0.44) | KMT2ACYP2A13LMNAACHERAB9A | |
| SCHEMBL14939089 | 0.88 | KMT2A (0.42) | KMT2ACYP2A13LMNAHTR7ACHE | |
| SCHEMBL14939708 | 0.88 | KMT2A (0.42) | KMT2ACYP2A13LMNAACHERAB9A | |
| SCHEMBL14939559 | 0.88 | KMT2A (0.42) | KMT2ACYP2A13LMNAHTR7ACHE | |
| SCHEMBL14939091 | 0.88 | KMT2A (0.42) | KMT2ACYP2A13LMNAHTR7ACHE | |
| SCHEMBL14939099 | 0.87 | KMT2A (0.43) | KMT2ACYP2A13LMNAACHERAB9A | |
| SCHEMBL14939536 | 0.86 | KMT2A (0.41) | KMT2ACYP2A13LMNAACHERAB9A | |
| SCHEMBL14938859 | 0.86 | ALDH1A1 (0.41) | KMT2ACYP2A13LMNAACHERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |