Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940304 | 0.90 | NPSR1 (0.46) | NPSR1LMNAKMT2ATRPC5MAPT | |
| SCHEMBL14939217 | 0.88 | NPSR1 (0.48) | NPSR1FAAHKMT2AMAPT | |
| SCHEMBL14939940 | 0.88 | NPSR1 (0.47) | NPSR1ADORA2AADORA1CYP2D6LMNA | |
| SCHEMBL14939130 | 0.88 | NPSR1 (0.47) | NPSR1ADORA2AADORA1CYP2D6LMNA | |
| SCHEMBL14940151 | 0.87 | MEN1 (0.44) | NPSR1CYP2D6DRD2KMT2AHTR7 | |
| SCHEMBL14939571 | 0.87 | NPSR1 (0.49) | NPSR1ADORA2AADORA1LMNAKMT2A | |
| SCHEMBL14939341 | 0.85 | NPSR1 (0.65) | NPSR1LMNADRD2KMT2ATRPC5 | |
| SCHEMBL14939274 | 0.84 | NPSR1 (0.44) | NPSR1ADORA2AADORA1LMNADRD2 | |
| SCHEMBL14939260 | 0.83 | NPSR1 (0.49) | NPSR1CYP2D6LMNADRD2DRD3 | |
| SCHEMBL14940076 | 0.82 | NPSR1 (0.46) | NPSR1ADORA2AADORA1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |