Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939426 | 0.87 | NPSR1 (0.67) | NPSR1SIGMAR1MMP2MMP9DRD2 | |
| SCHEMBL14939217 | 0.86 | NPSR1 (0.48) | NPSR1SIGMAR1MAPTKMT2AMEN1 | |
| SCHEMBL14939645 | 0.86 | SIGMAR1 (0.53) | NPSR1SIGMAR1DRD2HTR2BMAPT | |
| SCHEMBL14939259 | 0.86 | NPSR1 (0.65) | NPSR1SIGMAR1MMP2MMP9DRD2 | |
| SCHEMBL14939657 | 0.85 | NPSR1 (0.46) | NPSR1DRD2MAPTKMT2ALMNA | |
| SCHEMBL14940304 | 0.84 | NPSR1 (0.46) | NPSR1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL14940461 | 0.84 | NPSR1 (0.62) | NPSR1SIGMAR1MMP2MMP9DRD2 | |
| SCHEMBL14940151 | 0.82 | MEN1 (0.44) | NPSR1DRD2HTR2BL3MBTL1KMT2A | |
| SCHEMBL14939412 | 0.81 | NPSR1 (0.70) | NPSR1SIGMAR1MMP2MMP9DRD2 | |
| SCHEMBL14939776 | 0.81 | NPSR1 (0.59) | NPSR1SIGMAR1MMP2MMP9DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |