Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 known ✓ | P22455 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL151092 | 0.97 | LMNA (0.56) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL27419870 | 0.86 | LMNA (0.43) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL766910 | 0.83 | LMNA (0.46) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL27531088 | 0.83 | LMNA (0.67) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylamide SCHEMBL28010442 | 0.82 | ALDH1A1 (0.55) | LMNAALDH1A1TSHRZDHHC20ZDHHC2 | |
| Acrylic Acid SCHEMBL4644611 | 0.80 | LMNA (0.62) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL3399482 | 0.80 | LMNA (0.71) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL1147986 | 0.80 | — | — | |
| Acrylic Acid SCHEMBL30431258 | 0.80 | LMNA (0.71) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL29502206 | 0.80 | LMNA (0.71) | LMNAALDH1A1TSHRALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551366-B2 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| US-8388866-B2 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD. (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20120057269-A1 | CONDUCTIVE COMPOSITION AND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2012-03-08 | — | — | US | disclosed |
| US-8097184-B2 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20100097743-A1 | CONDUCTIVE COMPOSITION VAND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100098841-A1 | CONDUCTIVE COMPOSITION VAND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-7666326-B2 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20060047030-A1 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD | 2006-03-02 | — | — | US | disclosed |