Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939780 | 0.96 | NPSR1 (0.44) | NPSR1TP53MAPTLMNAOPRM1 | |
| SCHEMBL14939138 | 0.94 | NPSR1 (0.51) | NPSR1TP53MAPTLMNAOPRM1 | |
| SCHEMBL14939718 | 0.91 | TP53 (0.47) | NPSR1TP53MAPTLMNAHTT | |
| SCHEMBL14940177 | 0.88 | ALDH1A1 (0.48) | NPSR1TP53MAPTLMNAALDH1A1 | |
| SCHEMBL14939278 | 0.88 | NPSR1 (0.56) | NPSR1TP53MAPTLMNAOPRM1 | |
| SCHEMBL14939128 | 0.88 | NPSR1 (0.50) | NPSR1TP53MAPTLMNAHTT | |
| SCHEMBL14939262 | 0.88 | NPSR1 (0.53) | NPSR1TP53MAPTLMNAALDH1A1 | |
| SCHEMBL14939105 | 0.86 | NPSR1 (0.51) | NPSR1TP53MAPTLMNAHTT | |
| SCHEMBL14939842 | 0.86 | NPSR1 (0.50) | NPSR1TP53MAPTLMNAOPRM1 | |
| SCHEMBL14939270 | 0.86 | NPSR1 (0.61) | NPSR1TP53MAPTLMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |