Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544433 | 0.84 | MAPT (0.55) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL9563160 | 0.82 | KAT2B (0.60) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL9120897 | 0.79 | KAT2B (0.57) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL29111881 | 0.77 | MAPT (0.54) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL869207 | 0.75 | KAT2B (0.55) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL8718178 | 0.74 | MAPT (0.70) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL16861185 | 0.73 | NPC1 (0.72) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9820324 | 0.72 | MAPT (0.63) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL20798658 | 0.72 | MAPT (0.63) | MAPTSMN1; SMN2NPC1RAB9AKAT2B | |
| SCHEMBL9781715 | 0.72 | KAT2B (0.64) | MAPTSMN1; SMN2NPC1RAB9AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9578944-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-28 | — | — | US | disclosed |
| US-9565915-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-20150265513-A1 | METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR | L'OREAL (FR) | 2015-09-24 | — | — | US | disclosed |
| US-20140326270-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2014-11-06 | — | — | US | disclosed |
| US-20140305464-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2014-10-16 | — | — | US | disclosed |
| EP-2775992-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'Oréal (FR) | 2014-09-17 | — | — | EP | disclosed |
| EP-2775991-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'Oréal (FR) | 2014-09-17 | — | — | EP | disclosed |
| WO-2014074825-A1 | METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR | L'OREAL (FR) | 2014-05-15 | — | — | WO | disclosed |
| WO-2013071194-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013071192-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013071196-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013071191-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265513-A1 | METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR | COXFA4L2, TYR, COX5A | MAPT 2207/4885SMN1; SMN2 4619/4885NPC1 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.