SCHEMBL149407

SCHEMBL149407

O=C(O)/C=C/c1ccc(OC(=O)C=Cc2ccc(O)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.72
CA7 P43166 5/20 0.72
CA9 Q16790 5/20 0.72
CA14 Q9ULX7 5/20 0.72
AKR1B10 O60218 5/20 0.72
AKR1B1 P15121 5/20 0.72
CA1 P00915 4/20 0.72
CA2 P00918 4/20 0.72
TYR P14679 3/20 0.72
CA4 P22748 2/20 0.72
CA6 P23280 2/20 0.72
CA5A P35218 2/20 0.72
CA5B Q9Y2D0 2/20 0.72
ESR1 P03372 2/20 0.72
CA3 P07451 1/20 0.72
PKM P14618 1/20 0.72
DPP4 P27487 1/20 0.72
HCAR2 Q8TDS4 1/20 0.72
ESR2 Q92731 1/20 0.72
KMT2A Q03164 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679710 1.00 CA12 (0.72) CA12CA7CA9CA14AKR1B10
SCHEMBL5966380 1.00 CA12 (0.72) CA12CA7CA9CA14AKR1B10
SCHEMBL29009143 0.93 CA12 (0.67) CA12CA7CA9CA14AKR1B10
SCHEMBL14634511 0.88 KMT2A (0.68) CA12CA7CA9CA14AKR1B10
SCHEMBL28903591 0.88 KMT2A (0.78) CA12CA7CA9CA14AKR1B10
SCHEMBL30825756 0.88 KMT2A (0.73) CA12CA7CA9CA14AKR1B10
SCHEMBL14634510 0.88 KMT2A (0.68) CA12CA7CA9CA14AKR1B10
SCHEMBL29009142 0.88 KMT2A (0.73) CA12CA7CA9CA14AKR1B10
SCHEMBL8816786 0.87 KMT2A (0.59) CA12CA7CA9CA14AKR1B10
SCHEMBL8816792 0.87 KMT2A (0.59) CA12CA7CA9CA14AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120058540-A1 Probiotic Enriched and Low Organic Acid Food Products COMPAGNIE GERVAIS DANONE (FR) 2012-03-08 US disclosed
US-20100086646-A1 PROBIOTIC-CONTAINING FOOD PRODUCT AND A PROTONATED WEAK MONOACID COMPAGNIE GERVAIS DANONE (FR) 2010-04-08 US disclosed