Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811033 | 0.85 | POLB (0.55) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| SCHEMBL44233 | 0.85 | POLB (0.55) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| SCHEMBL503092 | 0.85 | POLB (0.55) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| SCHEMBL44234 | 0.85 | POLB (0.55) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL10655824 | 0.83 | POLB (0.54) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL10655830 | 0.83 | POLB (0.54) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL9641235 | 0.83 | POLB (0.54) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL10353563 | 0.82 | POLB (0.53) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL10353564 | 0.82 | POLB (0.53) | POLBGAAALDH1A1SMN1; SMN2FDPS | |
| SCHEMBL10005876 | 0.79 | POLB (0.47) | POLBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013071049-A1 | GRAMICIDIN A MUTANTS THAT FUNCTION AS ANTIBIOTICS WITH IMPROVED SOLUBILITY AND REDUCED TOXICITY | TRUSTEES OF BOSTON COLLEGE (US) | 2013-05-16 | — | — | WO | disclosed |