SCHEMBL44234

SCHEMBL44234

CC(Nc1ccccn1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.55
FDPS P14324 1/20 0.53
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
PKM P14618 2/20 0.52
LMNA P02545 2/20 0.49
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 2/20 0.49
ADORA3 P0DMS8 1/20 0.49
PIM1 P11309 1/20 0.49
ADORA2A P29274 1/20 0.49
ADORA2B P29275 1/20 0.49
ADORA1 P30542 1/20 0.49
FLT3 P36888 1/20 0.49
PIM3 Q86V86 1/20 0.49
AURKB Q96GD4 1/20 0.49
KDM4E B2RXH2 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6811033 1.00 POLB (0.55) POLBFDPSNPC1RAB9APKM
SCHEMBL503092 1.00 POLB (0.55) POLBFDPSNPC1RAB9APKM
SCHEMBL44233 1.00 POLB (0.55) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10655824 0.98 POLB (0.54) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL9641235 0.98 POLB (0.54) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10655830 0.98 POLB (0.54) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10353563 0.97 POLB (0.53) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10353564 0.97 POLB (0.53) POLBFDPSNPC1RAB9APKM
Maleic Acid SCHEMBL28620058 0.92 POLB (0.49) POLBFDPSNPC1RAB9APKM
SCHEMBL10434510 0.89 LMNA (0.52) POLBFDPSNPC1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6084 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 US claimed
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US claimed
US-20250332223-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2025-10-30 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
US-20250277012-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2025-09-04 US claimed
US-12377135-B2 GHRH antagonists for use in a method of treating sarcoidosis UNIVERSITY OF MIAMI (US) 2025-08-05 US claimed
US-12358948-B2 Neurotensinergic agonists and methods of using same preventing or treating pain SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2025-07-15 US claimed
WO-2025128149-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-19 WO claimed
US-20250186630-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING PEPTIDES VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-12 US claimed
US-20250122239-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2025-04-17 US claimed
EP-0370453-A2 Peptides having a Brady kinine-inhibiting activity HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0370382-A2 Urea dipeptide derivatives with a renin-inhibiting activity, process to produce them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0329013-A2 Renin-inhibiting amino acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
EP-0310015-A2 Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed
EP-0225386-A1 BRADYKININ ANTAGONIST PEPTIDES NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) 1987-06-16 EP claimed
WO-1986007263-A1 BRADYKININ ANTAGONIST PEPTIDES STEWART JOHN M 1986-12-18 WO claimed