SCHEMBL44233

SCHEMBL44233

C[C@H](Nc1ccccn1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.55
FDPS P14324 1/20 0.53
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
PKM P14618 2/20 0.52
LMNA P02545 2/20 0.49
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 2/20 0.49
ADORA3 P0DMS8 1/20 0.49
PIM1 P11309 1/20 0.49
ADORA2A P29274 1/20 0.49
ADORA2B P29275 1/20 0.49
ADORA1 P30542 1/20 0.49
FLT3 P36888 1/20 0.49
PIM3 Q86V86 1/20 0.49
AURKB Q96GD4 1/20 0.49
KDM4E B2RXH2 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6811033 1.00 POLB (0.55) POLBFDPSNPC1RAB9APKM
SCHEMBL503092 1.00 POLB (0.55) POLBFDPSNPC1RAB9APKM
SCHEMBL44234 1.00 POLB (0.55) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10655824 0.98 POLB (0.54) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL9641235 0.98 POLB (0.54) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10655830 0.98 POLB (0.54) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10353563 0.97 POLB (0.53) POLBFDPSNPC1RAB9APKM
Hydrochloric Acid SCHEMBL10353564 0.97 POLB (0.53) POLBFDPSNPC1RAB9APKM
Maleic Acid SCHEMBL28620058 0.92 POLB (0.49) POLBFDPSNPC1RAB9APKM
SCHEMBL10434510 0.89 LMNA (0.52) POLBFDPSNPC1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7980 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 US claimed
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 US claimed
EP-4711004-A2 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2026-03-18 EP claimed
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US claimed
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US claimed
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 US claimed
EP-4658374-A1 METHODS FOR PREPARING CRYSTALLINE PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Janssen Pharmaceutica NV (BE) 2025-12-10 EP claimed
EP-4648849-A1 NMU RECEPTOR 2 AGONISTS Boehringer Ingelheim International GmbH (DE) 2025-11-19 EP claimed
WO-2025226506-A1 MONO- AND DUAL-AGONIST COMPOUNDS OF HUMAN GLP1R AND GIPR FOR OBESITY & T2DM PROTAGONIST THERAPEUTICS, INC. (US) 2025-10-30 WO claimed
EP-0370453-A2 Peptides having a Brady kinine-inhibiting activity HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0370382-A2 Urea dipeptide derivatives with a renin-inhibiting activity, process to produce them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0329013-A2 Renin-inhibiting amino acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
EP-0310015-A2 Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed
EP-0225386-A1 BRADYKININ ANTAGONIST PEPTIDES NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) 1987-06-16 EP claimed
WO-1986007263-A1 BRADYKININ ANTAGONIST PEPTIDES STEWART JOHN M 1986-12-18 WO claimed