Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL2854389 | 0.96 | CA2 (0.40) | CA2LMNA | |
| Phosphoric Acid SCHEMBL5963629 | 0.96 | — | — | |
| Phosphoric Acid SCHEMBL2592618 | 0.96 | CA2 (0.46) | CA2LMNASLC34A1FDPS | |
| Phosphoric Acid SCHEMBL28156364 | 0.85 | CA2 (0.38) | CA2 | |
| Phosphoric Acid SCHEMBL28801388 | 0.83 | TSHR (0.50) | CA2LMNASLC34A1FDPS | |
| Phosphoric Acid SCHEMBL15675953 | 0.82 | CA2 (0.35) | CA2 | |
| Phosphoric Acid SCHEMBL28390234 | 0.82 | CA2 (0.35) | CA2 | |
| Phosphoric Acid SCHEMBL28868403 | 0.80 | CA2 (0.40) | CA2LMNA | |
| Phosphoric Acid SCHEMBL721013 | 0.80 | CA2 (0.40) | CA2LMNA | |
| Phosphoric Acid SCHEMBL10833922 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013071074-A1 | METHODS OF PRODUCING BUTADIENE | INVISTA NORTH AMERICA S.A. R.L. (US) | 2013-05-16 | — | — | WO | claimed |
| CN-108026214-B | Vinyl isomerase-dehydratase, enol-dehydratase, linalool-dehydratase and/or crotyl alcohol dehydratase, and preparation and use thereof | 基因组股份公司 | 2021-03-02 | — | — | CN | disclosed |
| WO-2013071074-A1 | METHODS OF PRODUCING BUTADIENE | INVISTA NORTH AMERICA S.A. R.L. (US) | 2013-05-16 | — | — | WO | disclosed |