Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336025 | 0.81 | RECQL (0.37) | RECQLNPC1RAB9ACPB2POLB | |
| SCHEMBL335564 | 0.76 | RECQL (0.39) | RECQLNPC1RAB9ACPB2POLB | |
| SCHEMBL113168 | 0.75 | RECQL (0.42) | RECQLNPC1RAB9APOLBPDXK | |
| SCHEMBL4171181 | 0.75 | TSHR (0.42) | RECQLNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL17013487 | 0.73 | DPP4 (0.37) | RECQLNPC1RAB9ACPB2POLB | |
| SCHEMBL335605 | 0.72 | RECQL (0.39) | RECQLNPC1RAB9APOLBPDXK | |
| SCHEMBL9649790 | 0.72 | CPB2 (0.50) | RECQLNPC1RAB9ACPB2POLB | |
| SCHEMBL27692700 | 0.71 | CPB2 (0.32) | RECQLCPB2 | |
| SCHEMBL14944013 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL16116517 | 0.69 | ESR1 (0.33) | RECQLNPC1RAB9ACPB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091936-B1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA LP (US) | 2013-05-15 | — | — | EP | disclosed |