⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26133433 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL25239775 | 0.79 | — | — | |
| SCHEMBL1535731 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL55906 | 0.75 | — | — | |
| SCHEMBL17996233 | 0.75 | — | — | |
| SCHEMBL25769700 | 0.75 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL17967412 | 0.73 | — | — | |
| SCHEMBL3128207 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL18496344 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL18059974 | 0.73 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186554-B2 | Non-fused tricyclic compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| WO-2020181386-A1 | FLUORINATED BENZO[F]BENZIMIDAZOL-4-9-DIONE IUM DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR USE AS SURVIVIN SUPPRESSANTS | TRILLIUM THERAPEUTICS INC. (CA) | 2020-09-17 | — | — | WO | disclosed |
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2020-02-27 | — | — | US | disclosed |
| EP-2591674-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-15 | — | — | EP | disclosed |