Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PI4KA | P42356 | 2/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790293 | 0.79 | ALDH1A1 (0.69) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL3867774 | 0.75 | XDH (0.77) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL29862834 | 0.75 | XDH (0.77) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL3868624 | 0.75 | XDH (0.56) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL13790449 | 0.75 | XDH (0.56) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL13790275 | 0.75 | XDH (0.63) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL13790393 | 0.74 | NPC1 (1.00) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL3868865 | 0.73 | KDM4E (0.75) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL130407 | 0.73 | PI4KA (1.00) | XDHKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL3876415 | 0.73 | XDH (0.73) | XDHKDM4EHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1827444-B1 | MNK1 OR MNK2 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2013-05-15 | — | — | EP | disclosed |