SCHEMBL14944615

SCHEMBL14944615

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nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ NANP Q8TBE9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16103775 0.87 L3MBTL1 (0.43) L3MBTL1NANP
SCHEMBL16438247 0.84 L3MBTL1 (0.45) L3MBTL1NANP
SCHEMBL29338118 0.84 L3MBTL1 (0.48) L3MBTL1NANP
SCHEMBL17471042 0.81 L3MBTL1 (0.45) L3MBTL1NANP
SCHEMBL14944587 0.80 L3MBTL1 (0.30) L3MBTL1
SCHEMBL17117576 0.79 NANP (0.52) L3MBTL1NANP
SCHEMBL16135482 0.79 NANP (0.52) L3MBTL1NANP
SCHEMBL15746561 0.79 NANP (0.52) L3MBTL1NANP
SCHEMBL27391399 0.79 NANP (0.52) L3MBTL1NANP
SCHEMBL15133464 0.78 L3MBTL1 (0.46) L3MBTL1NANP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160297846-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. (US) 2016-10-13 — — US disclosed
US-9221858-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2015-12-29 — — US disclosed
US-20150038693-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. (US) 2015-02-05 — — US disclosed
US-8840926-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2014-09-23 — — US disclosed
US-20130122094-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL, INC. (US) 2013-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160297846-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 L3MBTL1 1717/4885NANP 37/4885
US-20130122094-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 L3MBTL1 1717/4885NANP 37/4885
US-20150038693-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 L3MBTL1 1717/4885NANP 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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