SCHEMBL27391399

SCHEMBL27391399

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nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 3/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ ASGR1 P07306 1/20 0.33
▸ NEU2 Q9Y3R4 3/20 0.33
▸ NEU4 Q8WWR8 2/20 0.33
▸ NEU3 Q9UQ49 2/20 0.33
▸ NEU1 Q99519 1/20 0.33
▸ MAG P20916 2/20 0.33
▸ SELL P14151 1/20 0.32
▸ SELP P16109 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17117576 1.00 NANP (0.52) NANPL3MBTL1ASGR1NEU2NEU4
SCHEMBL16135482 1.00 NANP (0.52) NANPL3MBTL1ASGR1NEU2NEU4
SCHEMBL15746561 1.00 NANP (0.52) NANPL3MBTL1ASGR1NEU2NEU4
SCHEMBL18231344 0.88 L3MBTL1 (0.42) NANPL3MBTL1ASGR1NEU2NEU4
SCHEMBL24246810 0.88 NANP (0.41) NANPL3MBTL1ASGR1MAGALDH1A1
SCHEMBL27391404 0.88 NANP (0.41) NANPL3MBTL1ASGR1MAGALDH1A1
SCHEMBL25576480 0.88 NANP (0.41) NANPL3MBTL1ASGR1MAGALDH1A1
SCHEMBL21016580 0.88 L3MBTL1 (0.41) NANPL3MBTL1NEU3MAG
SCHEMBL18495194 0.86 L3MBTL1 (0.40) NANPL3MBTL1
SCHEMBL16174059 0.85 NANP (0.40) NANPL3MBTL1ASGR1NEU2NEU4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216490-A1 Autoantigens Engineered to Suppress Autoimmune Response ADAXION THERAPEUTICS, INC. 2024-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216490-A1 Autoantigens Engineered to Suppress Autoimmune Response CD74, MICA, HLA-DRB1 NANP 1086/4885L3MBTL1 2848/4885ASGR1 190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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