SCHEMBL14944734

SCHEMBL14944734

O=COc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
KDM4E B2RXH2 7/20 0.44
HSD17B10 Q99714 6/20 0.44
HPGD P15428 5/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 6/20 0.42
TSHR P16473 2/20 0.42
ESR1 P03372 1/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
HMGB1 P09429 1/20 0.42
GGT1 P19440 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16351584 0.84 MAPK1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL933092 0.82 KDM4E (0.58) CA12CA1CA2CA7CA9
SCHEMBL10022811 0.82 CDC25B (0.60) KDM4EHSD17B10ALDH1A1TDP1AKR1C3
SCHEMBL8948126 0.80 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL29395127 0.80 HTT (0.53) CA12CA1CA2CA7CA9
SCHEMBL143861 0.80 HTT (0.53) CA12CA1CA2CA7CA9
SCHEMBL17540386 0.80 KDM4E (0.43) KDM4EHSD17B10HPGDMAPTMAPK1
SCHEMBL26158622 0.80 PTGER1 (0.46) KDM4EHSD17B10HPGDMAPTMAPK1
SCHEMBL17718224 0.80 ALDH1A1 (0.50) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL5251616 0.79 CA12 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217109-B2 Polymer-stabilised liquid-crystal media and displays MERCK PATENT GMBH (DE) 2015-12-22 US disclosed
US-20130119311-A1 POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-05-16 US disclosed
CN-101715471-B Resin composition for sliding member and rolling bearing NTN TOYO BEARING CO LTD 2013-04-17 CN disclosed
CN-101490605-B Liquid crystal panel and liquid crystal display device NITTO DENKO CORP 2012-05-30 CN disclosed
CN-101611335-B Method for production of long optical laminate, and liquid crystal panel NITTO DENKO CORP. (JP) 2011-12-14 CN disclosed
CN-101715471-A resin composition for sliding member and rolling bearing NTN TOYO BEARING CO LTD 2010-05-26 CN disclosed
CN-101611335-A The manufacture method of long optical laminate and liquid crystal panel NITTO DENKO CORP (JP) 2009-12-23 CN disclosed
CN-101529319-A Liquid crystal panel and liquid crystal display device NITTO DENKO CORP (JP) 2009-09-09 CN disclosed
CN-101523251-A Optical laminate, polarizing plate, image displays, and process for production of the laminate NITTO DENKO CORP (JP) 2009-09-02 CN disclosed
CN-101490605-A Liquid crystal panel and liquid crystal display device NITTO DENKO CORP (JP) 2009-07-22 CN disclosed
CN-101326461-A Liquid crystal panel and liquid crystal display device NITTO DENKO CORP (JP) 2008-12-17 CN disclosed
CN-101101411-A Liquid crystal panel and liquid crystal display NITTO DENKO CORP (JP) 2008-01-09 CN disclosed