SCHEMBL933092

SCHEMBL933092

O=COc1ccccc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.58
HSD17B10 Q99714 6/20 0.58
HPGD P15428 6/20 0.58
MAPT P10636 2/20 0.58
ALDH1A1 P00352 9/20 0.55
HMGB1 P09429 2/20 0.55
NAPRT Q6XQN6 2/20 0.55
ESR1 P03372 1/20 0.55
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55
TSHR P16473 1/20 0.55
GGT1 P19440 1/20 0.55
PTGS1 P23219 1/20 0.55
PTGS2 P35354 1/20 0.55
BLM P54132 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
USP2 O75604 1/20 0.53
PDE3A Q14432 1/20 0.53
ALOX15 P16050 1/20 0.52
HTT P42858 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL11130138 0.94 KDM4E (0.53) KDM4EHSD17B10HPGDMAPTALDH1A1
1,2-Dichlorobenzene SCHEMBL28253435 0.91 ALDH1A1 (0.55) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL17718224 0.89 ALDH1A1 (0.50) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL14927366 0.85 KDM4E (0.47) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL6151817 0.82 ELANE (0.54) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL14944734 0.82 CA12 (0.46) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL32687438 0.82 KDM4E (0.56) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL4209791 0.82 KDM4E (0.56) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL11490196 0.82 CTNNB1 (0.56) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL11314323 0.82 LMNA (0.53) KDM4EHSD17B10HPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417930-B A kind of biomass acid material and preparation method thereof 南京汉旗新材料科技有限公司 2019-11-05 CN claimed
CN-110098443-A A kind of method of carbon coating waste lithium cell negative electrode material 浙江卡波恩新材料有限公司 2019-08-06 CN claimed
CN-109777398-A A kind of polychrome tunable radiation emitting composite material of N doping carbon dots coordination rare earth and its polychrome light altering film for agriculture of preparation 山东农业大学 2019-05-21 CN claimed
CN-107417930-A A kind of biomass acid material and preparation method thereof 南京汉旗新材料科技有限公司 2017-12-01 CN claimed
CN-105154069-A Multi-colored adjustable light-emitting material of nitrogen-doped carbon dot coordination rare earth and preparation method thereof UNIV SHANDONG AGRICULTURE 2015-12-16 CN claimed
CN-103467766-B Rapid preparation method of totally-biodegradable composite membrane with nanometer silver on surface UNIV ZHEJIANG SCIENCE & TECH 2015-03-18 CN claimed
CN-103467766-A Rapid preparation method of totally-biodegradable composite membrane with nanometer silver on surface UNIV ZHEJIANG SCIENCE & TECH 2013-12-25 CN claimed
US-20240242967-A1 Polymer For Forming Metal-Containing Film, Composition For Forming Metal-Containing Film, And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
US-20220184083-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-06-16 US disclosed
EP-4007748-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2022-06-08 EP disclosed
WO-2021110680-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-06-10 WO disclosed
CN-107417930-B A kind of biomass acid material and preparation method thereof 南京汉旗新材料科技有限公司 2019-11-05 CN disclosed
CN-107417930-B A kind of biomass acid material and preparation method thereof 南京汉旗新材料科技有限公司 2019-11-05 CN disclosed
WO-1992000808-A1 METHOD OF INTERCALATION OF PEROVSKITIC PARTICLES IN THE FORM OF PILLARS INTO LAYERED CLAYS POMONIS PHILIP (GR) 1992-01-23 WO disclosed
US-4933355-A ALDOSE REDUCTASE INHIBITORS SANKYO COMPANY LIMITED (JP) 1990-06-12 US disclosed
CN-1006381-B Process for the preparation of N-substituted alpha-amino acids MONSANTO CO (US) 1990-01-10 CN disclosed
EP-0337819-A1 Thiazole derivatives, their preparation and their use in the treatment of diabetes complications Sankyo Company Limited (JP) 1989-10-18 EP disclosed
US-4680308-A ANTITUMOR, ANTIINFLAMMATORY AND TRYPANOCIDAL AGENTS ANDRULIS RESEARCH CORPORATION (US) 1987-07-14 US disclosed
EP-0228298-A2 Stable soluble 1,2-diamino-cyclohexane platinum complexes ANDRULIS RESEARCH CORPORATION (US) 1987-07-08 EP disclosed
CN-85109396-A The preparation method of the a-amino acid that N-replaces 1986-10-08 CN disclosed