Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944764 | 0.89 | TSHR (0.41) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL10040732 | 0.83 | ELANE (0.41) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL10040692 | 0.80 | ELANE (0.41) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL10234472 | 0.78 | MAOB (0.35) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL23926511 | 0.77 | ALDH1A1 (0.56) | TDP1POLBALDH1A1L3MBTL1 | |
| SCHEMBL10064080 | 0.77 | ELANE (0.43) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL9299347 | 0.76 | KMT2A (0.41) | TSHRPOLBALDH1A1L3MBTL1 | |
| SCHEMBL16559822 | 0.76 | ELANE (0.43) | TDP1POLBAPEX1HTTELANE | |
| SCHEMBL10234473 | 0.75 | MAPT (0.35) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL10234471 | 0.75 | ELANE (0.51) | TSHRTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |