Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944800 | 0.81 | POLB (0.39) | TSHRMAPTCYP3A4ALDH1A1MAPK1 | |
| SCHEMBL17354427 | 0.79 | THRB (0.36) | THRBTSHRMAPTCYP3A4ALDH1A1 | |
| SCHEMBL19759256 | 0.77 | MAPT (0.40) | THRBMAPTGAAALDH1A1MAPK1 | |
| SCHEMBL13171633 | 0.77 | LCK (0.40) | THRBTSHRMAPTCYP3A4ALDH1A1 | |
| SCHEMBL17354426 | 0.76 | THRB (0.41) | THRBTSHRCYP3A4ALDH1A1MAPK1 | |
| SCHEMBL19759246 | 0.76 | THRB (0.40) | THRBMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL19082936 | 0.75 | MAPT (0.38) | THRBMAPTCYP3A4MAPK1KDM4E | |
| SCHEMBL15946522 | 0.75 | KMT2A (0.39) | THRBMAPTCYP3A4ALDH1A1TP53 | |
| SCHEMBL19771198 | 0.75 | CYP2D6 (0.39) | KDM4ECYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL13806822 | 0.75 | TAS1R3 (0.36) | THRBMAPTCYP3A4HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |