Formetorex

Formetorex

SCHEMBL14944822

C[C@@H](Cc1ccccc1)NC=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
EPHX1 P07099 1/20 0.66
SIGMAR1 Q99720 7/20 0.59
SLC18A2 Q05940 1/20 0.59
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
CYP3A4 P08684 2/20 0.51
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51
CYP2C19 P33261 1/20 0.51
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formetorex SCHEMBL1812509 1.00 TAAR1 (1.00) TAAR1MEN1KMT2AEPHX1SIGMAR1
Formetorex SCHEMBL2780459 1.00 TAAR1 (1.00) TAAR1MEN1KMT2AEPHX1SIGMAR1
SCHEMBL8763948 0.90 TAAR1 (0.81) TAAR1MEN1KMT2AEPHX1SIGMAR1
SCHEMBL10439420 0.82 KMT2A (0.70) TAAR1MEN1KMT2AEPHX1NPC1
SCHEMBL10439384 0.82 KMT2A (0.70) TAAR1MEN1KMT2AEPHX1NPC1
SCHEMBL14944821 0.82 KMT2A (0.70) TAAR1MEN1KMT2AEPHX1NPC1
SCHEMBL8763940 0.82 TAAR1 (0.69) TAAR1MEN1KMT2AEPHX1SIGMAR1
SCHEMBL11077995 0.81 TAAR1 (0.68) TAAR1MEN1KMT2AEPHX1SIGMAR1
SCHEMBL12280099 0.81 KMT2A (0.68) TAAR1MEN1KMT2AEPHX1SIGMAR1
SCHEMBL11294468 0.81 TAAR1 (0.68) TAAR1MEN1KMT2AEPHX1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017098533-A2 PROCESS FOR PREPARATION OF LISDEXAMPHETAMINE SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2017-06-15 WO disclosed
US-8871789-B2 Method of preventing or treating viral infection THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2014-10-28 US disclosed
US-20130123344-A1 METHOD OF PREVENTING OR TREATING VIRAL INFECTION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123344-A1 METHOD OF PREVENTING OR TREATING VIRAL INFECTION KDM1B, KDM1A, KDM2A TAAR1 3873/4885MEN1 3013/4885KMT2A 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.