Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.59 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formetorex SCHEMBL14944822 | 1.00 | TAAR1 (1.00) | TAAR1MEN1KMT2AEPHX1SIGMAR1 | |
| Formetorex SCHEMBL1812509 | 1.00 | TAAR1 (1.00) | TAAR1MEN1KMT2AEPHX1SIGMAR1 | |
| SCHEMBL8763948 | 0.90 | TAAR1 (0.81) | TAAR1MEN1KMT2AEPHX1SIGMAR1 | |
| SCHEMBL10439420 | 0.82 | KMT2A (0.70) | TAAR1MEN1KMT2AEPHX1NPC1 | |
| SCHEMBL10439384 | 0.82 | KMT2A (0.70) | TAAR1MEN1KMT2AEPHX1NPC1 | |
| SCHEMBL14944821 | 0.82 | KMT2A (0.70) | TAAR1MEN1KMT2AEPHX1NPC1 | |
| SCHEMBL8763940 | 0.82 | TAAR1 (0.69) | TAAR1MEN1KMT2AEPHX1SIGMAR1 | |
| SCHEMBL11077995 | 0.81 | TAAR1 (0.68) | TAAR1MEN1KMT2AEPHX1SIGMAR1 | |
| SCHEMBL12280099 | 0.81 | KMT2A (0.68) | TAAR1MEN1KMT2AEPHX1SIGMAR1 | |
| SCHEMBL11294468 | 0.81 | TAAR1 (0.68) | TAAR1MEN1KMT2AEPHX1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107892670-B | Method for synthesizing formamide derivative through cobalt-catalyzed formylation reaction | 湘潭大学 | 2019-12-13 | — | — | CN | claimed |
| US-8710268-B2 | Method for the hydrolysis of substituted formylamines into substituted amines | BOBYLEV MIKHAIL (US) | 2014-04-29 | — | — | US | claimed |
| US-20130046111-A1 | Method for the Hydrolysis of Substituted Formylamines into Substituted Amines | BOBYLEV MIKHAIL (US) | 2013-02-21 | — | — | US | claimed |
| EP-2175854-A1 | IMPROVED METHOD FOR THE SYNTHESIS OF SUBSTITUTED FORMYLAMINES AND SUBSTITUTED AMINES | University Of North Dakota Research Foundation (US) | 2010-04-21 | — | — | EP | claimed |
| US-20090143622-A1 | Method For The Synthesis Of Substituted Formylamines And Substituted Amines | BOBYLEV MIKHAIL | 2009-06-04 | — | — | US | claimed |
| WO-2009018353-A1 | IMPROVED METHOD FOR THE SYNTHESIS OF SUBSTITUTED FORMYLAMINES AND SUBSTITUTED AMINES | UNIVERSITY OF NORTH DAKOTA RESEARCH FOUNDATION (US) | 2009-02-05 | — | — | WO | claimed |
| EP-1442006-B1 | PREPARATION OF AMPHETAMINES FROM PHENYLPROPANOLAMINES | BOEHRINGER INGELHEIM CHEMICALS (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1442006-A2 | PREPARATION OF AMPHETAMINES FROM PHENYLPROPANOLAMINES | Boehringer Ingelheim Chemicals, Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037843-A2 | PREPARATION OF AMPHETAMINES FROM PHENYLPROPANOLAMINES | BOEHRINGER INGELHEIM CHEMICALS, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
| US-6399828-B1 | ACYLATION OF PHENYLPROPANOLAMINE; CATALYTIC HYDROGENATION | BOEHRINGER INGELHEIM CHEMICALS, INC. | 2002-06-04 | — | — | US | disclosed |