Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | AOC1 | P19801 | 7/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 4/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632786 | 0.83 | — | — | |
| SCHEMBL31336445 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL26917203 | 0.81 | AOC1 (0.61) | LOXL2AOC1AOC3CYP2A6CYP2E1 | |
| Hydrochloric Acid SCHEMBL18764671 | 0.81 | AOC1 (0.61) | LOXL2AOC1AOC3CYP2A6CYP2E1 | |
| SCHEMBL873728 | 0.81 | CYP2E1 (0.49) | LOXL2AOC1AOC3CYP2A6CYP2E1 | |
| SCHEMBL6628774 | 0.79 | TKT (0.39) | LOXL2AOC1AOC3CYP2A6CYP2E1 | |
| SCHEMBL21983945 | 0.78 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL18924363 | 0.78 | TDP1 (0.43) | AOC1AOC3CYP2A6CYP2E1CYP2C8 | |
| SCHEMBL30824586 | 0.77 | LOXL2 (0.73) | TAAR1LOXL2HTR6AOC1AOC3 | |
| SCHEMBL27140192 | 0.77 | LOXL2 (0.73) | TAAR1LOXL2HTR6AOC1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | MMAB, PTMS, DNPEP | TAAR1 4174/4885LOXL2 2215/4885HTR6 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.