SCHEMBL1494512

SCHEMBL1494512

CC(C)[Si](C)(C)[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1727634 0.76
SCHEMBL29803 0.70
SCHEMBL1107768 0.67
SCHEMBL15341 0.65
SCHEMBL4389530 0.65
SCHEMBL301273 0.63
SCHEMBL1107772 0.63
Fluoride SCHEMBL15321052 0.63
SCHEMBL23706776 0.60
SCHEMBL1494408 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112368292-B Phosphoramidite compound, preparation method and application thereof 深圳华大生命科学研究院 2024-05-17 CN claimed
CN-112368292-A Phosphoramidite compound, preparation method and application thereof 深圳华大生命科学研究院 2021-02-12 CN claimed
WO-2020010560-A1 PHOSPHORAMIDITE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳华大生命科学研究院 2020-01-16 WO claimed
EP-1640378-A1 Metallocene catalysts comprising monocyclic multisiloxy substituted cyclopentadienyl group(s) for the polymerisation of olefins Borealis Technology Oy (FI) 2006-03-29 EP claimed
EP-1149086-B1 NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES LEK TOVARNA FARMACEVTSKIH (SI) 2004-05-12 EP claimed
US-6509479-B1 To produce simvastatin LEK PHARMACEUTICALS D.D. (SI) 2003-01-21 US claimed
EP-1149086-A1 NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES Lek Pharmaceutical and Chemical Co. D.D. (SI) 2001-10-31 EP claimed
WO-2000046217-A1 NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES LEK PHARMACEUTICALS AND CHEMICAL COMPANY D.D. (SI) 2000-08-10 WO claimed
US-5650523-A REACTION IN SOLVENTS TO FORM HYDROXY GROUPS MERCK & CO., INC. (US) 1997-07-22 US claimed
EP-0315954-B1 Pattern-forming material and pattern formation method TORAY SILICONE CO (JP) 1995-11-22 EP claimed
EP-0444888-B1 Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one MERCK & CO INC (US) 1995-02-08 EP claimed
EP-0444888-A1 Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one MERCK & CO. INC. (US) 1991-09-04 EP claimed
US-4985342-A Semiconductors, Integrated Circuits TORAY SILICONE COMPANY, LTD. (JP) 1991-01-15 US claimed
EP-0315954-A2 Pattern-forming material and pattern formation method TORAY SILICONE COMPANY, LIMITED (JP) 1989-05-17 EP claimed
CN-112368292-B Phosphoramidite compound, preparation method and application thereof 深圳华大生命科学研究院 2024-05-17 CN disclosed
CN-112368292-A Phosphoramidite compound, preparation method and application thereof 深圳华大生命科学研究院 2021-02-12 CN disclosed
US-10854818-B2 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-12-01 US disclosed
EP-0251827-A2 New cyclic ether derivatives, their preparation and their use Sankyo Company Limited (JP) 1988-01-07 EP disclosed
US-4634706-A BRAIN METABOLISM SANKYO COMPANY LIMITED (JP) 1987-01-06 US disclosed
EP-0143557-A2 Griseolic acid derivatives, and their use SANKYO COMPANY LIMITED (JP) 1985-06-05 EP disclosed